Belladonna, scientifically known as Atropa belladonna, is a perennial herbaceous plant that has been historically associated with medicinal and, in some cases, toxic properties. Also known as deadly nightshade, belladonna has a rich history of use in various traditional medicines, though its toxicity has limited its contemporary applications. Cultivating belladonna requires careful attention to detail, knowledge of its growing conditions, and adherence to safety precautions due to its potent alkaloids. In this article, we will explore the steps involved in belladonna cultivation.